Omicron Probably in N.Y.C. Earlier Than Detected, Wastewater Data Suggests

The Four Percent


Omicron was probably present in New York City’s wastewater more than a week before the first case of the new variant was detected in the United States, according to a new report from the Centers for Disease Control and Prevention and researchers across the country.

The samples suggest that someone in New York City may have had the Omicron variant as early as Nov. 21, four days before South African scientists first announced cases of the variant and ten days before the first U.S. case was reported. Researchers in California and Texas also found evidence of Omicron in wastewater samples from late November.

The findings suggest that at the time, the Omicron variant was more widespread in the United States than the case data alone would indicate, and provide more evidence that wastewater surveillance can serve as an early warning system about the spread of new variants.

“At first it was uncertain whether this variant was going to come to the United States,” said Alexandria Boehm, an environmental engineer at Stanford and an author of the paper. “The wastewater answered that question way before the clinical samples could, and the answer was yes.”

Dr. Boehm’s team took a different approach in California, using P.C.R. tests capable of detecting some of Omicron’s specific mutations. They got their first hit on Nov. 26, from a sample collected in Merced the previous day, Dr. Boehm said. They got another on a sample collected in Sacramento on Nov. 30.

The first confirmed case of Omicron in the U.S. was announced on Dec. 1.

“We have really rapid turnaround and really frequent sampling,” Dr. Boehm said. She added, “This just gives information way earlier than clinical sequencing can.”


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